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The Challenge of Staging Breast Cancer With PET/CT in the Era of COVID Vaccination

Brown, AH; Shah, S; Groves, AM; Wan, S; Malhotra, A; (2021) The Challenge of Staging Breast Cancer With PET/CT in the Era of COVID Vaccination. Clinical Nuclear Medicine , 46 (12) pp. 1006-1010. 10.1097/RLU.0000000000003683. Green open access

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Abstract

We report a case series of biopsy-proven reactive axillary lymph nodes, which were avid on FDG PET/CT in breast cancer patients post COVID-19 vaccination. With 4 cases presenting in a consecutive 10-day period, it became apparent that metabolically active axillary lymphadenopathy is an adverse effect of COVID-19 vaccines, currently being deployed worldwide. This may lead to patients undergoing unnecessary biopsy. We have started taking a COVID-19 vaccine status history before PET/CT. If enlarged/metabolically active axillary nodes are identified in the ipsilateral vaccinated arm, then axillary ultrasound at 4 weeks is suggested.

Type: Article
Title: The Challenge of Staging Breast Cancer With PET/CT in the Era of COVID Vaccination
Location: United States
Open access status: An open access version is available from UCL Discovery
DOI: 10.1097/RLU.0000000000003683
Publisher version: https://doi.org/10.1097/RLU.0000000000003683
Language: English
Additional information: This version is the author accepted manuscript. For information on re-use, please refer to the publisher’s terms and conditions.
UCL classification: UCL
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Medical Sciences
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Medical Sciences > Div of Medicine
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Medical Sciences > Div of Medicine > Experimental and Translational Medicine
URI: https://discovery.ucl.ac.uk/id/eprint/10135666
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