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Non-coding RNAs in endodontic disease

Galicia, J; Khan, AA; (2022) Non-coding RNAs in endodontic disease. Seminars in Cell & Developmental Biology , 124 pp. 82-84. 10.1016/j.semcdb.2021.07.006. Green open access

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Abstract

The immunocompetence and regeneration potential of the dental pulp and its surrounding apical tissues have been investigated extensively in the field of endodontics. While research on the role of non-coding RNAs in these tissues is still in its infancy, it is envisioned that improved understanding of the regulatory function of ncRNAs in pulpal and periapical immune response will help prevent or treat endodontic disease. Of particular importance is the role of these RNAs in regenerating the dentin-pulp complex. In this review, we highlight recent progress on the role of non-coding RNAs in the immune response to endodontic infection as well as the repair and regenerative response to injury.

Type: Article
Title: Non-coding RNAs in endodontic disease
Location: England
Open access status: An open access version is available from UCL Discovery
DOI: 10.1016/j.semcdb.2021.07.006
Publisher version: https://doi.org/10.1016/j.semcdb.2021.07.006
Language: English
Additional information: This version is the author accepted manuscript. For information on re-use, please refer to the publisher’s terms and conditions.
Keywords: Dental, Epigenetic, MicroRNA, Non-coding RNA, SiRNAs
UCL classification: UCL
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Medical Sciences
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Medical Sciences > Eastman Dental Institute
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Medical Sciences > Eastman Dental Institute > Restorative Dental Sciences
URI: https://discovery.ucl.ac.uk/id/eprint/10134990
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