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Tissue mimicking materials for imaging and therapy phantoms: a review

McGarry, CK; Grattan, LJ; Ivory, AM; Leek, F; Liney, GP; Liu, Y; Miloro, P; ... Clark, CH; + view all (2020) Tissue mimicking materials for imaging and therapy phantoms: a review. Physics in Medicine & Biology , 65 (23) 10.1088/1361-6560/abbd17. Green open access

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Abstract

Tissue mimicking materials (TMMs), typically contained within phantoms, have been used for many decades in both imaging and therapeutic applications. This review investigates the specifications that are typically being used in development of the latest TMMs. The imaging modalities that have been investigated focus around CT, mammography, SPECT, PET, MRI and ultrasound. Therapeutic applications discussed within the review include radiotherapy, thermal therapy and surgical applications. A number of modalities were not reviewed including optical spectroscopy, optical imaging and planar x-rays. The emergence of image guided interventions and multimodality imaging have placed an increasing demand on the number of specifications on the latest TMMs. Material specification standards are available in some imaging areas such as ultrasound. It is recommended that this should be replicated for other imaging and therapeutic modalities. Materials used within phantoms have been reviewed for a series of imaging and therapeutic applications with the potential to become a testbed for cross-fertilization of materials across modalities. Deformation, texture, multimodality imaging and perfusion are common themes that are currently under development.

Type: Article
Title: Tissue mimicking materials for imaging and therapy phantoms: a review
Open access status: An open access version is available from UCL Discovery
DOI: 10.1088/1361-6560/abbd17
Publisher version: https://doi.org/10.1088/1361-6560/abbd17
Language: English
Additional information: Original content from this work may be used under the terms of the Creative Commons Attribution 4.0 license. Any further distribution of this work must maintain attribution to the author(s) and the title of the work, journal citation and DOI.
UCL classification: UCL
UCL > Provost and Vice Provost Offices > UCL BEAMS
UCL > Provost and Vice Provost Offices > UCL BEAMS > Faculty of Engineering Science
UCL > Provost and Vice Provost Offices > UCL BEAMS > Faculty of Engineering Science > Dept of Med Phys and Biomedical Eng
URI: https://discovery.ucl.ac.uk/id/eprint/10134606
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