UCL Discovery
UCL home » Library Services » Electronic resources » UCL Discovery

Recent advances in biosensing approaches for point-of-care breast cancer diagnostics: challenges and future prospects

Joshi, A; Vishnu G. K., A; Sakorikar, T; Kamal, AM; Vaidya, JS; Pandya, HJ; (2021) Recent advances in biosensing approaches for point-of-care breast cancer diagnostics: challenges and future prospects. Nanoscale Advances 10.1039/d1na00453k. (In press). Green open access

[thumbnail of d1na00453k.pdf]
Preview
Text
d1na00453k.pdf - Published Version

Download (1MB) | Preview

Abstract

Timely and accurate diagnosis of breast cancer is essential for efficient treatment and the best possible survival rates. Biosensors have emerged as a smart diagnostic platform for the detection of biomarkers specific to the onset, recurrence, and therapeutic drug monitoring of breast cancer. There have been exciting recent developments, including significant improvements in the validation, sensitivity, specificity, and integration of sample processing steps to develop point-of-care (POC) integrated micro-total analysis systems for clinical settings. The present review highlights various biosensing modalities (electrical, optical, piezoelectric, mass, and acoustic sensing). It provides deep insights into their design principles, signal amplification strategies, and comparative performance analysis. Finally, this review emphasizes the status of existing integrated micro-total analysis systems (μ-TAS) for personalized breast cancer therapeutics and associated challenges and outlines the approach required to realize their successful translation into clinical settings.

Type: Article
Title: Recent advances in biosensing approaches for point-of-care breast cancer diagnostics: challenges and future prospects
Open access status: An open access version is available from UCL Discovery
DOI: 10.1039/d1na00453k
Publisher version: https://doi.org/10.1039/D1NA00453K
Language: English
Additional information: This article is licensed under a Creative Commons Attribution-NonCommercial 3.0 Unported Licence.
Keywords: Science & Technology, Physical Sciences, Technology, Chemistry, Multidisciplinary, Nanoscience & Nanotechnology, Materials Science, Multidisciplinary, Chemistry, Science & Technology - Other Topics, Materials Science, SURFACE-PLASMON RESONANCE, FREE ELECTROCHEMICAL DETECTION, DOPED SILICA NANOPARTICLES, LABEL-FREE DETECTION, SIGNAL AMPLIFICATION, GROWTH-FACTOR, ULTRASENSITIVE DETECTION, COLORIMETRIC DETECTION, QUANTUM DOTS, CARBON DOTS
UCL classification: UCL
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Medical Sciences
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Medical Sciences > Div of Surgery and Interventional Sci
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Medical Sciences > Div of Surgery and Interventional Sci > Department of Targeted Intervention
URI: https://discovery.ucl.ac.uk/id/eprint/10134536
Downloads since deposit
27Downloads
Download activity - last month
Download activity - last 12 months
Downloads by country - last 12 months

Archive Staff Only

View Item View Item