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Craniofacial growth and SITAR growth curve analysis

Patcas, R; Keller, H; Markic, G; Beit, P; Eliades, T; Cole, TJ; (2021) Craniofacial growth and SITAR growth curve analysis. European Journal of Orthodontics , Article cjab059. 10.1093/ejo/cjab059. (In press). Green open access

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EJO-2021-OA-0220.R2_Accepted_submission.pdf - Accepted version
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Abstract

BACKGROUND: SITAR (SuperImposition by Translation And Rotation) is a shape invariant growth curve model that effectively summarizes somatic growth in puberty. AIM: To apply the SITAR model to longitudinal mandibular growth data to clarify its suitability to facial growth analysis. SUBJECTS AND METHODS: 2D-cephalometric data on two mandibular measurements (AP: articulare–pogonion; CP: condylion–pogonion) were selected from the Denver Growth Study, consisting of longitudinal records (age range: 7.9–19.0 years) of females (sample size N: 21; number of radiographs n: 154) and males (N: 18; n: 137). The SITAR mixed effects model estimated, for each measurement and gender separately, a mean growth curve versus chronological age, along with mean age at peak velocity (APV) and peak velocity (PV), plus subject-specific random effects for PV and mean size. The models were also fitted versus Greulich–Pyle bone age. RESULTS: In males, mean APV occurred at 14.6 years (AP) and 14.4 years (CP), with mean PV 3.1 mm/year (AP) and 3.3 mm/year (CP). In females, APV occurred at 11.6 years (AP and CP), with mean PV 2.3 mm/year (AP) and 2.4 mm/year (CP). The models explained 95–96 per cent of the cross-sectional variance for males and 92–93 per cent for females. The random effects demonstrated standard deviations (SDs) in size of 5.6 mm for males and 3.9 mm for females, and SDs for PV between 0.3 and 0.5 mm/year. The bone age results were similar. CONCLUSION: The SITAR model is a useful tool to analyse epidemiological craniofacial growth based on cephalometric data and provides an array of information on pubertal mandibular growth and its variance in a concise manner.

Type: Article
Title: Craniofacial growth and SITAR growth curve analysis
Open access status: An open access version is available from UCL Discovery
DOI: 10.1093/ejo/cjab059
Publisher version: https://doi.org/10.1093/ejo/cjab059
Language: English
Additional information: This version is the author accepted manuscript. For information on re-use, please refer to the publisher’s terms and conditions.
Keywords: Diagnostic radiologic examination, face, mandible, puberty, gender, bone age, peak arterial velocity
UCL classification: UCL
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Population Health Sciences
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Population Health Sciences > UCL GOS Institute of Child Health
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Population Health Sciences > UCL GOS Institute of Child Health > Population, Policy and Practice Dept
URI: https://discovery.ucl.ac.uk/id/eprint/10134287
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