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An overview of the current medical literature on Zika virus

Hossein, F; (2020) An overview of the current medical literature on Zika virus. Biophysical Reviews , 12 (5) pp. 1133-1138. 10.1007/s12551-020-00748-8. Green open access

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Abstract

Zika virus is a member of the family of Flaviviridae, which is primarily spread to humans by mosquito bites. It has been linked to microcephaly in neonates, and as such, it poses a significant risk to human pregnancy. Zika virus infection is also implicated in other severe neurological disorders such as Guillain-Barre syndrome. There is currently no vaccine available to treat Zika virus disease, and as such, it represents a serious challenge to public health. Antigenic similarities between Zika and dengue can suggest artificially high infection rates of Zika within specific population groups. Here, we review recent literature and provide an update on the status of the Zika outbreak, including a description of available medical countermeasure options and current diagnosis methodology.

Type: Article
Title: An overview of the current medical literature on Zika virus
Location: Germany
Open access status: An open access version is available from UCL Discovery
DOI: 10.1007/s12551-020-00748-8
Publisher version: https://doi.org/10.1007/s12551-020-00748-8
Language: English
Additional information: This version is the author accepted manuscript. For information on re-use, please refer to the publisher’s terms and conditions.
Keywords: Aedes aegypti, Dengue, Flavivirus, Microcephaly, Mosquitos, Zika
UCL classification: UCL
UCL > Provost and Vice Provost Offices > UCL BEAMS
UCL > Provost and Vice Provost Offices > UCL BEAMS > Faculty of Engineering Science
UCL > Provost and Vice Provost Offices > UCL BEAMS > Faculty of Engineering Science > Dept of Chemical Engineering
URI: https://discovery.ucl.ac.uk/id/eprint/10133940
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