Blackstone, C;
Elwood, F;
Plun-Favreau, H;
Lewis, PA;
(2021)
Vesicle trafficking and pathways to neurodegeneration.
Molecular Neurodegeneration
, 16
(1)
, Article 56. 10.1186/s13024-021-00480-1.
Preview |
Text
s13024-021-00480-1.pdf - Published Version Download (963kB) | Preview |
Abstract
Neurodegenerative diseases, encompassing a diverse range of inherited and sporadic disorders characterised by progressive loss of relatively discrete neuronal populations, are a significant and increasing challenge to human health and the global economy [1]. Despite significant advances in our understanding of the underlying ætiology of diseases such as Alzheimer’s, Parkinson’s and Huntington’s, and intense efforts targeting the development of disease-modifying therapies for these disorders, for the majority of people living with neurodegenerative conditions the prognosis remains poor [2,3,4]. Improving our knowledge of the underlying causes of neuronal loss in these disorders with the goal of developing novel disease-modifying therapies is thus a top priority for research, patient and care-giver communities.
Archive Staff Only
 |
View Item |
