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Imaging and treatment of brain tumors through molecular targeting: Recent clinical advances

Zaccagna, F; Grist, JT; Quartuccio, N; Riemer, F; Fraioli, F; Caracò, C; Halsey, R; ... Gallagher, FA; + view all (2021) Imaging and treatment of brain tumors through molecular targeting: Recent clinical advances. European Journal of Radiology , 142 , Article 109842. 10.1016/j.ejrad.2021.109842. Green open access

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Abstract

Molecular imaging techniques have rapidly progressed over recent decades providing unprecedented in vivo characterization of metabolic pathways and molecular biomarkers. Many of these new techniques have been successfully applied in the field of neuro-oncological imaging to probe tumor biology. Targeting specific signaling or metabolic pathways could help to address several unmet clinical needs that hamper the management of patients with brain tumors. This review aims to provide an overview of the recent advances in brain tumor imaging using molecular targeting with positron emission tomography and magnetic resonance imaging, as well as the role in patient management and possible therapeutic implications.

Type: Article
Title: Imaging and treatment of brain tumors through molecular targeting: Recent clinical advances
Location: Ireland
Open access status: An open access version is available from UCL Discovery
DOI: 10.1016/j.ejrad.2021.109842
Publisher version: http://dx.doi.org/10.1016/j.ejrad.2021.109842
Language: English
Additional information: © 2021 The Authors. Published by Elsevier B.V. This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/).
Keywords: Brain tumor, Glioma, MRI, Molecular imaging, PET, Theranostics
UCL classification: UCL
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Medical Sciences
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Medical Sciences > Div of Medicine
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Medical Sciences > Div of Medicine > Department of Imaging
URI: https://discovery.ucl.ac.uk/id/eprint/10132476
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