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Capturing the Occult Central Retinal Artery Occlusion Using Optical Coherence Tomography

Balal, S; J'Bari, AS; Hassan, A; Sharma, A; Wagner, SK; Pasu, S; (2021) Capturing the Occult Central Retinal Artery Occlusion Using Optical Coherence Tomography. Current Eye Research 10.1080/02713683.2021.1921219. (In press).

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Abstract

AIMS: To report spectral-domain optical coherence tomography (OCT) findings in cases of impending or occult central retinal artery occlusion (CRAO) in which a diagnosis other than CRAO was made on initial presentation. METHODS: Retrospective, observational case series of patients diagnosed with CRAO for whom on initial presentation fundal examination and OCT findings were deemed unremarkable and/or a diagnosis other than CRAO was made. OCT images from the initial presentation were then reviewed for evidence of inner retinal ischaemia. RESULTS: In total, 214 cases of CRAO were identified. Eleven patients (5.14%) had been given an alternative initial diagnosis at their first presentation in casualty and were included. The age range was 20–84 years and 81% (9/11) were male. On review of initial OCT imaging performed in casualty, all cases had evidence of inner retinal ischaemia. Conclusions: CRAO is an ophthalmic emergency which leads to vision loss which is often irreversible. Examination of the fundus may be normal early in the course of the disease and therefore a timely diagnosis may be missed. This case series reports the OCT findings of inner retinal ischaemia in patients with occult or impending CRAO which may aid in the early diagnosis and referral to stroke services.

Type: Article
Title: Capturing the Occult Central Retinal Artery Occlusion Using Optical Coherence Tomography
DOI: 10.1080/02713683.2021.1921219
Publisher version: https://doi.org/10.1080/02713683.2021.1921219
Language: English
Additional information: This version is the author accepted manuscript. For information on re-use, please refer to the publisher’s terms and conditions.
Keywords: Central retinal artery occlusion; CRAO; retinal artery occlusion; RAO; spectral-domain optical coherence tomography; optical coherence tomography; OCT
UCL classification: UCL
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Brain Sciences
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Brain Sciences > Institute of Ophthalmology
URI: https://discovery.ucl.ac.uk/id/eprint/10131688
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