UCL Discovery
UCL home » Library Services » Electronic resources » UCL Discovery

Prostanoid receptors in GtoPdb v.2021.2

Clapp, L; Giembycz, M; Heinemann, A; Jones, RL; Narumiya, S; Norel, X; Sugimoto, Y; ... Yao, C; + view all (2021) Prostanoid receptors in GtoPdb v.2021.2. IUPHAR/BPS Guide to Pharmacology CITE , 2021 (2) 10.2218/gtopdb/f58/2021.2. Green open access

[thumbnail of Guide to prostaniod receptors 2021.pdf]
Preview
Text
Guide to prostaniod receptors 2021.pdf - Published Version

Download (7MB) | Preview

Abstract

Prostanoid receptors (nomenclature as agreed by the NC-IUPHAR Subcommittee on Prostanoid Receptors [694]) are activated by the endogenous ligands prostaglandins PGD2, PGE1, PGE2 , PGF2α, PGH2, prostacyclin [PGI2] and thromboxane A2. Differences and similarities between human and rodent prostanoid receptor orthologues, and their specific roles in pathophysiologic conditions are reviewed in [448]. Measurement of the potency of PGI2 and thromboxane A2 is hampered by their instability in physiological salt solution; they are often replaced by cicaprost and U46619, respectively, in receptor characterization studies.

Type: Article
Title: Prostanoid receptors in GtoPdb v.2021.2
Open access status: An open access version is available from UCL Discovery
DOI: 10.2218/gtopdb/f58/2021.2
Publisher version: https://doi.org/10.2218/gtopdb/f58/2021.2
Language: English
Additional information: This work is licensed under a Creative Commons Attribution-ShareAlike 4.0 International License (http://creativecommons.org/licenses/by-sa/4.0/).
UCL classification: UCL
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Population Health Sciences > Institute of Cardiovascular Science
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Population Health Sciences > Institute of Cardiovascular Science > Pre-clinical and Fundamental Science
URI: https://discovery.ucl.ac.uk/id/eprint/10131491
Downloads since deposit
20Downloads
Download activity - last month
Download activity - last 12 months
Downloads by country - last 12 months

Archive Staff Only

View Item View Item