Orlandi, M;
D'Aiuto, F;
Porter, SR;
Ciurtin, C;
(2020)
The Mouth and Lupus.
In:
Lupus: Diagnosis and Treatment.
(pp. 1-17).
Lupus UK: Romford, UK.
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Abstract
The oral cavity is often referred to as a “mirror of the body” and can be the first site with clinical signs of a sometimes distant systemic disease. The oral manifestations of various systemic conditions may precede or follow closely the involvement of other parts of the body and, in some instances, can be the dominant feature that warrants a particular emphasis upon investigation and/or treatment. Oral disease can sometimes be having the greatest negative impact upon a patient with systemic illness. The presence of oral ulcers (including nasopharyngeal ulcers) is one of the 11 criteria defined by the American College of Rheumatology for the diagnosis of systemic lupus erythematosus (SLE). A thorough examination of the oral tissues can provide useful information to clinicians for an early diagnosis of SLE. Oral lesions would normally improve if lupus is adequately controlled and their reoccurrence is often an indicator of a new disease flare-up. A wide spectrum of oral signs and symptoms caused by lupus has been described and might be related not only to the disease itself, but also to concomitant secondary conditions or be the effect of different medications.
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