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Moderate aortic stenosis: What is it and when should we intervene?

Badiani, S; Bhattacharyya, S; Aziminia, N; Treibel, TA; Lloyd, G; (2021) Moderate aortic stenosis: What is it and when should we intervene? Interventional Cardiology Review , 16 , Article e09. 10.15420/ICR.2021.04. Green open access

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Abstract

Current guidelines recommend aortic valve replacement in patients with severe aortic stenosis in the presence of symptoms or a left ventricular ejection fraction <50%. However, patients with less than severe aortic stenosis may also experience symptoms and recent literature suggests that the prognosis is not as benign as previously reported. There are no recommendations for patients with moderate aortic stenosis and left ventricular dysfunction, despite the high associated morbidity and mortality. There is also some evidence that these patients may benefit from early aortic valve intervention. It is recognised that aortic stenosis not only affects the valve but also has a complex myocardial response. This review discusses the natural history of moderate aortic stenosis along with the role of multimodality imaging in risk stratification in these patients.

Type: Article
Title: Moderate aortic stenosis: What is it and when should we intervene?
Open access status: An open access version is available from UCL Discovery
DOI: 10.15420/ICR.2021.04
Publisher version: http://dx.doi.org/10.15420/ICR.2021.04
Language: English
Additional information: This work is open access under the CC-BY-NC 4.0 License which allows users to copy, redistribute and make derivative works for non-commercial purposes, provided the original work is cited correctly
Keywords: Aortic stenosis, biology, progression, echocardiography, imaging, interventions, outcomes
UCL classification: UCL
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Population Health Sciences > Institute of Cardiovascular Science
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Population Health Sciences > Institute of Cardiovascular Science > Clinical Science
URI: https://discovery.ucl.ac.uk/id/eprint/10129367
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