Chari, A;
Mallucci, C;
Whitelaw, A;
Aquilina, K;
(2021)
Intraventricular haemorrhage and posthaemorrhagic ventricular dilatation: moving beyond CSF diversion.
Child's Nervous System
10.1007/s00381-021-05206-8.
(In press).
Preview |
Text
Chari_Intraventricular haemorrhage and posthaemorrhagic ventricular dilatation- moving beyond CSF diversion_AOP.pdf - Published Version Download (4MB) | Preview |
Abstract
Advances in medical care have led to more premature babies surviving the neonatal period. In these babies, germinal matrix haemorrhage (GMH), intraventricular haemorrhage (IVH) and posthaemorrhagic ventricular dilatation (PHVD) are the most important determinants of long-term cognitive and developmental outcomes. In this review, we discuss current neurosurgical management of IVH and PHVD, including the importance of early diagnosis of PHVD, thresholds for intervention, options for early management through the use of temporising measures and subsequent definitive CSF diversion. We also discuss treatment options for the evolving paradigm to manage intraventricular blood and its breakdown products. We review the evidence for techniques such as drainage, irrigation, fibrinolytic therapy (DRIFT) and neuroendoscopic lavage in the context of optimising cognitive, neurodevelopmental and quality of life outcomes in these premature infants.
Type: | Article |
---|---|
Title: | Intraventricular haemorrhage and posthaemorrhagic ventricular dilatation: moving beyond CSF diversion |
Open access status: | An open access version is available from UCL Discovery |
DOI: | 10.1007/s00381-021-05206-8 |
Publisher version: | http://dx.doi.org/10.1007/s00381-021-05206-8 |
Language: | English |
Additional information: | Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/. |
Keywords: | Germinal matrix haemorrhage, Intraventricular haemorrhage, Posthaemorrhagic ventricular dilatation, Temporising device, Premature, Neuroendoscopic lavage, ENDOSCOPIC 3RD VENTRICULOSTOMY, CHOROID-PLEXUS CAUTERIZATION, BIRTH-WEIGHT INFANTS, PRETERM INFANTS, NEURODEVELOPMENTAL OUTCOMES, PREMATURE-INFANTS, HYDROCEPHALUS, TRENDS, RATES |
UCL classification: | UCL UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Population Health Sciences > UCL GOS Institute of Child Health UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Population Health Sciences > UCL GOS Institute of Child Health > Developmental Neurosciences Dept |
URI: | https://discovery.ucl.ac.uk/id/eprint/10128932 |
Archive Staff Only
View Item |