UCL Discovery
UCL home » Library Services » Electronic resources » UCL Discovery

Saphenous Vein Vasa Vasorum as a Potential Target for Perivascular Fat-Derived Factors

Loesch, A; Dashwood, MR; (2020) Saphenous Vein Vasa Vasorum as a Potential Target for Perivascular Fat-Derived Factors. Brazilian Journal of Cardiovascular Surgery , 35 (6) pp. 964-969. 10.21470/1678-9741-2020-0031. Green open access

[thumbnail of Loesch_v35n6a17.pdf]
Preview
Text
Loesch_v35n6a17.pdf - Published version

Download (2MB) | Preview

Abstract

Perivascular adipose tissue (PVAT) is a source of factors affecting vasomotor tone with the potential to play a role in the performance of saphenous vein (SV) bypass grafts. As these factors have been described as having constrictor or relaxant effects, they may be considered either beneficial or detrimental. The close proximity of PVAT to the adventitia provides an environment whereby adipose tissue-derived factors may affect the vasa vasorum, a microvascular network providing the vessel wall with oxygen and nutrients. Since medial ischaemia promotes aspects of graft occlusion the involvement of the PVAT/vasa vasorum axis in vein graft patency should be considered.

Type: Article
Title: Saphenous Vein Vasa Vasorum as a Potential Target for Perivascular Fat-Derived Factors
Open access status: An open access version is available from UCL Discovery
DOI: 10.21470/1678-9741-2020-0031
Publisher version: https:/doi.org/10.21470/1678-9741-2020-0031
Language: English
Additional information: This is an open-access article distributed under the terms of the Creative Commons Attribution License
Keywords: Saphenous Vein, Adventitia, Perivascular Fat, Vasa Vasorum, Microvessels, Nutrient
UCL classification: UCL
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Medical Sciences
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Medical Sciences > Div of Medicine
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Medical Sciences > Div of Surgery and Interventional Sci
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Medical Sciences > Div of Surgery and Interventional Sci > Department of Surgical Biotechnology
URI: https://discovery.ucl.ac.uk/id/eprint/10128179
Downloads since deposit
5Downloads
Download activity - last month
Download activity - last 12 months
Downloads by country - last 12 months

Archive Staff Only

View Item View Item