Daich Varela, M;
Esener, B;
Hashem, SA;
Cabral de Guimaraes, TA;
Georgiou, M;
Michaelides, M;
(2021)
Structural evaluation in inherited retinal diseases.
British Journal of Ophthalmology
10.1136/bjophthalmol-2021-319228.
(In press).
Preview |
Text
bjophthalmol-2021-319228.full.pdf - Published Version Download (1MB) | Preview |
Abstract
Ophthalmic genetics is a field that has been rapidly evolving over the last decade, mainly due to the flourishing of translational medicine for inherited retinal diseases (IRD). In this review, we will address the different methods by which retinal structure can be objectively and accurately assessed in IRD. We review standard-of-care imaging for these patients: colour fundus photography, fundus autofluorescence imaging and optical coherence tomography (OCT), as well as higher-resolution and/or newer technologies including OCT angiography, adaptive optics imaging, fundus imaging using a range of wavelengths, magnetic resonance imaging, laser speckle flowgraphy and retinal oximetry, illustrating their utility using paradigm genotypes with on-going therapeutic efforts/trials.
| Type: | Article |
|---|---|
| Title: | Structural evaluation in inherited retinal diseases. |
| Location: | England |
| Open access status: | An open access version is available from UCL Discovery |
| DOI: | 10.1136/bjophthalmol-2021-319228 |
| Publisher version: | http://dx.doi.org/10.1136/bjophthalmol-2021-319228 |
| Language: | English |
| Additional information: | This is an open access article distributed in accordance with the Creative Commons Attribution 4.0 Unported (CC BY 4.0) license, which permits others to copy, redistribute, remix, transform and build upon this work for any purpose, provided the original work is properly cited, a link to the licence is given, and indication of whether changes were made. See: https://creativecommons.org/licenses/by/4.0/. |
| Keywords: | Clinical trial, dystrophy, genetics, imaging, retina |
| UCL classification: | UCL UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Brain Sciences UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Brain Sciences > Institute of Ophthalmology |
| URI: | https://discovery.ucl.ac.uk/id/eprint/10128133 |
Archive Staff Only
 |
View Item |
