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Patient-specific prediction of long-term outcomes will change stroke rehabilitation for the better.

Walford, I; Rondina, JM; Ward, N; (2021) Patient-specific prediction of long-term outcomes will change stroke rehabilitation for the better. Journal of Neurology, Neurosurgery and Psychiatry 10.1136/jnnp-2020-325981. (In press). Green open access

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Abstract

Stroke is the most common cause of neurological disability and yet our ability to predict long-term outcomes remains poor. The paper by Selles et al1 used upper limb outcomes from 450 patients with first-time ischaemic stroke to take a refreshingly different approach to the prediction problem. First, allowing repeated clinical measures to contribute to the prediction acknowledges what most clinicians already know—that rate of clinical change is helpful in prognostication. Second, rather than predict outcome at a single future time point, they have created likely recovery trajectories (with CIs) for individual patients. Third, access to this predictive model is freely available online, so that stroke services around the world can more accurately begin to make predictions of individual recovery. Although the current approach concerns upper limb recovery, the principle should apply to all domains.

Type: Article
Title: Patient-specific prediction of long-term outcomes will change stroke rehabilitation for the better.
Location: England
Open access status: An open access version is available from UCL Discovery
DOI: 10.1136/jnnp-2020-325981
Publisher version: http://dx.doi.org/10.1136/jnnp-2020-325981
Language: English
Additional information: This version is the author accepted manuscript. For information on re-use, please refer to the publisher’s terms and conditions.
Keywords: rehabilitation, stroke
UCL classification: UCL
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Brain Sciences
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Brain Sciences > UCL Queen Square Institute of Neurology
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Brain Sciences > UCL Queen Square Institute of Neurology > Brain Repair and Rehabilitation
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Brain Sciences > UCL Queen Square Institute of Neurology > Clinical and Movement Neurosciences
URI: https://discovery.ucl.ac.uk/id/eprint/10126421
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