Donoghue, K;
(2021)
The correlates and extent of prescribing of medications for alcohol relapse prevention in England.
Addiction
, 116
(11)
pp. 3019-3026.
10.1111/add.15502.
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Abstract
AIMS: To determine the pattern and extent of prescribing of medications for alcohol relapse prevention (ARP) in England. DESIGN: Cross-sectional. SETTING: Specialist drug and alcohol treatment providers in England reporting to the National Drug Treatment Monitoring System. PARTICIPANTS: Service users aged 18+, alcohol the primary substance of dependence, completing a treatment journey between April 2013 and March 2016 (N=188,152). MEASUREMENTS: Prescription of medications for ARP during a treatment journey. Data on service users' demographics, treatment and clinical characteristics were extracted. FINDINGS: The rate of prescribing of medications for ARP was 2.1% in 2013/14, 6.8% in 2014/15 and 7.8% in 2015/16. A greater likelihood of prescription was associated with treatment journey year (2014/15; Adjusted Odds Ratio (ORadj )=3.269, 95% Confidence Intervals (CI)=3.044-3.510, 2015/16; ORadj =3.823, CI=3.560-4.106), age (25-34; ORadj =1.622, CI=1.380-1.907, 35-54; ORadj =1.901, CI=1.628-2.220 or 55+; ORadj =1.700, CI=1.446-1.999), female gender (ORadj =1.129, CI=1.077-1.184), white ethnicity (ORadj =1.219, CI=1.077-1.380), regional prevalence of alcohol dependence (middle rate; ORadj =1.121, CI=1.024-1.228), severity of alcohol dependence (moderate dependence without complex needs; ORadj =1.329, CI=1.244-1.419, severe dependence without complex needs; ORadj =1.308, CI=1.188-1.441, moderate/severe dependence with complex needs; ORadj =1.131, CI=1.020-1.255), treatment setting (inpatient; ORadj =10.512, CI=9.950-11.104, Primary Care; ORadj =2.264, CI=2.050-2.500, residential; ORadj =3.216, CI=2.807-3.685), prior treatment for alcohol dependence (ORadj =1.242, CI=1.183-1.304), longer treatment journey (ORadj =1.002, CI=1.002-1.002), more drinking days in the prior 28 days (ORadj =1.021, CI=1.018-1.024) and drinking a higher number of alcohol units in the prior 28 days (ORadj =1.002 CI=1.001-1.004). Living in a region of England with the lowest alcohol prevalence was associated with a lower likelihood of prescription of medication for ARP (ORadj =0.491, CI=0.436-0.552). CONCLUSIONS: In England, medications for alcohol relapse prevention are rarely prescribed (e.g., 7.8% in 2015/16) and those prescriptions appear to be associated with specific service user demographics, treatment, and clinical characteristics.
| Type: | Article |
|---|---|
| Title: | The correlates and extent of prescribing of medications for alcohol relapse prevention in England |
| Location: | England |
| Open access status: | An open access version is available from UCL Discovery |
| DOI: | 10.1111/add.15502 |
| Publisher version: | https://doi.org/10.1111/add.15502 |
| Language: | English |
| Additional information: | This version is the author accepted manuscript. For information on re-use, please refer to the publisher’s terms and conditions. |
| Keywords: | Acamprosate, Alcohol Dependence, Alcohol Relapse Prevention, Disulfiram, Logistic Regression, Naltrexone, Prescribing |
| UCL classification: | UCL UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Brain Sciences UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Brain Sciences > Div of Psychology and Lang Sciences UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Brain Sciences > Div of Psychology and Lang Sciences > Clinical, Edu and Hlth Psychology |
| URI: | https://discovery.ucl.ac.uk/id/eprint/10126412 |
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