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Pulmonary Metastasectomy in Colorectal Cancer: has the randomized controlled trial brought enough reliable evidence to convince believers in metastasectomy to reconsider their oncological practice?

Van Raemdonck, D; Treasure, T; Van Cutsem, E; Macbeth, F; (2021) Pulmonary Metastasectomy in Colorectal Cancer: has the randomized controlled trial brought enough reliable evidence to convince believers in metastasectomy to reconsider their oncological practice? European Journal of Cardio-Thoracic Surgery , 59 (3) pp. 517-521. 10.1093/ejcts/ezaa450. Green open access

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Abstract

In February 2019, the US Society of Thoracic Surgeons (STS) published their Expert Consensus Document on Pulmonary Metastasectomy, stating that there has never been a randomized trial on the subject but that ‘metastatic disease survival is assumed to be zero’. This would mean that all survival beyond 5 years is attributable to metastasectomy [1]. The randomized controlled trial (RCT) Pulmonary Metastasectomy in Colorectal Cancer (PulMiCC) was published in May 2020 [2]. PulMiCC contradicted those 2 statements: there was now an RCT and the control survival was not zero. Dirk Van Raemdonck...

Type: Article
Title: Pulmonary Metastasectomy in Colorectal Cancer: has the randomized controlled trial brought enough reliable evidence to convince believers in metastasectomy to reconsider their oncological practice?
Location: Germany
Open access status: An open access version is available from UCL Discovery
DOI: 10.1093/ejcts/ezaa450
Publisher version: https://doi.org/10.1093/ejcts/ezaa450
Language: English
Additional information: This version is the author accepted manuscript. For information on re-use, please refer to the publisher's terms and conditions.
UCL classification: UCL
UCL > Provost and Vice Provost Offices > UCL BEAMS
UCL > Provost and Vice Provost Offices > UCL BEAMS > Faculty of Maths and Physical Sciences
UCL > Provost and Vice Provost Offices > UCL BEAMS > Faculty of Maths and Physical Sciences > Dept of Mathematics
UCL > Provost and Vice Provost Offices > UCL BEAMS > Faculty of Maths and Physical Sciences > Dept of Mathematics > Clinical Operational Research Unit
URI: https://discovery.ucl.ac.uk/id/eprint/10125597
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