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A model for in vitro evaluation of overlapping connections between devices used in the endovascular repair of popliteal aneurysms

Locks, G; Roesler, C; Horn, F; Gindri, I; Wurdemann, H; Silveira, P; (2021) A model for in vitro evaluation of overlapping connections between devices used in the endovascular repair of popliteal aneurysms. Journal of Testing and Evaluation (In press). Green open access

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Abstract

This work proposes a new methodology to investigate the potential for disconnection (Type III endoleak) of pairs of overlapped endoprostheses in a popliteal model vessel after a cyclic physiologic load, for three different overlap lengths. A multiaxial fatigue accelerated testing was designed to mimic the physiological loads and movements to which the peripheral arteries are submitted during gait. The experiment design was based on principles from technical standards ASTM F2477-07 and ASTM F2942-13. Migration and disconnection were monitored by DIC (Digital Image Correlation) for three different overlap lengths (20, 30 and 40mm). The testing method proposed in this work was efficient to provide a simulated environment to evaluate the influence of gait biomechanics on overlapped endoprosthesis disconnection. Obtained results demonstrated minimal or absence of relevant migration between the endoprosthesis, range -0.06 to 0,34 millimeters. The proposed methodology was verified as a valuable tool to investigate the influence of the biomechanical environment which the devices are subjected to on the migration of overlapped endoprosthesis. It may become a new alternative to study the pre-clinical in vitro performance of single endoprosthesis or multiple connected devices with different overlapped regions.

Type: Article
Title: A model for in vitro evaluation of overlapping connections between devices used in the endovascular repair of popliteal aneurysms
Open access status: An open access version is available from UCL Discovery
Publisher version: https://www.astm.org/DIGITAL_LIBRARY/JOURNALS/TEST...
Language: English
Additional information: This version is the author accepted manuscript. For information on re-use, please refer to the publisher’s terms and conditions.
Keywords: popliteal artery, aneurysm, endovascular procedures, endoleak, mechanical testing
UCL classification: UCL
UCL > Provost and Vice Provost Offices > UCL BEAMS
UCL > Provost and Vice Provost Offices > UCL BEAMS > Faculty of Engineering Science
UCL > Provost and Vice Provost Offices > UCL BEAMS > Faculty of Engineering Science > Dept of Mechanical Engineering
URI: https://discovery.ucl.ac.uk/id/eprint/10125069
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