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Visualizing anatomically registered data with Brainrender

Claudi, F; Tyson, AL; Petrucco, L; Margrie, TW; Portugues, R; Branco, T; (2021) Visualizing anatomically registered data with Brainrender. eLife , 10 , Article e65751. 10.7554/eLife.65751. (In press). Green open access

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Abstract

Three-dimensional (3D) digital brain atlases and high-throughput brain wide imaging techniques generate large multidimensional datasets that can be registered to a common reference frame. Generating insights from such datasets depends critically on visualization and interactive data exploration, but this a challenging task. Currently available software is dedicated to single atlases, model species or data types, and generating 3D renderings that merge anatomically registered data from diverse sources requires extensive development and programming skills. Here, we present brainrender: an open-source Python package for interactive visualization of multidimensional datasets registered to brain atlases. Brainrender facilitates the creation of complex renderings with different data types in the same visualization and enables seamless use of different atlas sources. High-quality visualizations can be used interactively and exported as high-resolution figures and animated videos. By facilitating the visualization of anatomically registered data, brainrender should accelerate the analysis, interpretation, and dissemination of brain-wide multidimensional data.

Type: Article
Title: Visualizing anatomically registered data with Brainrender
Location: England
Open access status: An open access version is available from UCL Discovery
DOI: 10.7554/eLife.65751
Publisher version: http://dx.doi.org/10.7554/eLife.65751
Language: English
Additional information: © 2021, Claudi et al. This article is distributed under the terms of the Creative Commons Attribution License permitting unrestricted use and redistribution provided that the original author and source are credited.
Keywords: neuroscience, none
UCL classification: UCL
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Life Sciences
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Life Sciences > The Sainsbury Wellcome Centre
URI: https://discovery.ucl.ac.uk/id/eprint/10125004
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