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Time Is of the Essence: Early Detection of Incipient Alzheimer Pathology

Barkhof, BF; Pressman, PS; (2021) Time Is of the Essence: Early Detection of Incipient Alzheimer Pathology. Neurology 10.1212/WNL.0000000000011739. (In press).

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Abstract

With the possible advent of disease-modifying treatments by targeting β-amyloid metabolism or deposition, it becomes crucial to identify individuals at risk for Alzheimer dementia as early as possible, preferably before the onset of overt cognitive impairment. Accessibility of screening tools in underserved areas will be important, despite a lack of neurologic or neuropsychological expertise. Long wait times, which are now common for dementia specialist care, will become even more unacceptable if the wait means delaying a disease-modifying treatment. Given the prevalence of Alzheimer disease and related disorders, such screening is likely to place high demands on the medical system.

Type: Article
Title: Time Is of the Essence: Early Detection of Incipient Alzheimer Pathology
Location: United States
DOI: 10.1212/WNL.0000000000011739
Publisher version: https://doi.org/10.1212/WNL.0000000000011739
Language: English
Additional information: This version is the author accepted manuscript. For information on re-use, please refer to the publisher's terms and conditions.
UCL classification: UCL
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Brain Sciences
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Brain Sciences > UCL Queen Square Institute of Neurology
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Brain Sciences > UCL Queen Square Institute of Neurology > Brain Repair and Rehabilitation
URI: https://discovery.ucl.ac.uk/id/eprint/10123441
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