De Francesco, D;
Sabin, CA;
Winston, A;
Mallon, PWG;
Anderson, J;
Boffito, M;
Doyle, ND;
... Kunisaki, KM; + view all
(2021)
Agreement between self-reported and objective measures of sleep in people with HIV and lifestyle-similar HIV-negative individuals.
AIDS
, 35
(7)
pp. 1051-1060.
10.1097/QAD.0000000000002852.
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Abstract
OBJECTIVES: To evaluate the agreement between self-reported sleep measures and insomnia with objectively-measured sleep parameters in people with HIV (PWH) and HIV-negative individuals. DESIGN: Cross-sectional analysis of PWH and lifestyle-similar HIV-negative individuals. METHODS: Self-reported measures included time spent in bed, sleep onset latency and a validated insomnia questionnaire. Objective measures were assessed via 7-days/nights of actigraphy data to determine average and intra-individual variability of several sleep measures (including time spent in bed and onset latency). Spearman's correlation coefficient and Cohen's κ were used to assess agreement between self-reported and actigraphy-assessed measures. Associations between insomnia and actigraphy-assessed sleep parameters were evaluated using partial least-square discriminant analysis (PLS-DA). RESULTS: We found fair correlation between self-reported and actigraphy-assessed time spent in bed in 342 PWH (rs = 0.46) and 119 HIV-negative individuals (rs = 0.48). Among PWH, the correlation did not differ by age, education, depressive symptoms and self-reported insomnia (all p > 0.05), but was stronger in males (p = 0.05) and in those with BMI ≥ 25 kg/m2 (p < 0.001). Agreement between self-reported and actigraphy-assessed sleep onset latency was poor in both PWH (κ = 0.002, p = 0.49) and HIV-negative individuals (κ = 0.009, p = 0.65). According to PLS-DA, self-reported insomnia most strongly correlated with intra-individual variability of sleep duration, movement index and efficiency. CONCLUSIONS: We report poor-to-fair agreement between self-reported and actigraphy-assessed sleep measures in PWH. Insomnia symptoms correlated with regularity of sleep duration, quality and efficiency. These findings highlight the importance of both patient-reported and objective measures of daily sleep variation, for better understanding sleep disorders in PWH.
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