Vanhille-Campos, C;
Šarić, A;
(2021)
Modelling the dynamics of vesicle reshaping and scission under osmotic shocks.
Soft Matter
10.1039/D0SM02012E.
(In press).
Preview |
Text
d0sm02012e.pdf - Published Version Download (3MB) | Preview |
Abstract
We study the effects of osmotic shocks on lipid vesicles via coarse-grained molecular dynamics simulations by explicitly considering the solute in the system. We find that depending on their nature (hypo- or hypertonic) such shocks can lead to bursting events or engulfing of external material into inner compartments, among other morphology transformations. We characterize the dynamics of these processes and observe a separation of time scales between the osmotic shock absorption and the shape relaxation. Our work consequently provides an insight into the dynamics of compartmentalization in vesicular systems as a result of osmotic shocks, which can be of interest in the context of early proto-cell development and proto-cell compartmentalisation.
| Type: | Article |
|---|---|
| Title: | Modelling the dynamics of vesicle reshaping and scission under osmotic shocks |
| Location: | England |
| Open access status: | An open access version is available from UCL Discovery |
| DOI: | 10.1039/D0SM02012E |
| Publisher version: | https://dx.doi/10.1039/D0SM02012E |
| Language: | English |
| Additional information: | This Open Access Article is licensed under a Creative Commons Attribution-Non Commercial 3.0 Unported Licence |
| UCL classification: | UCL UCL > Provost and Vice Provost Offices > UCL BEAMS UCL > Provost and Vice Provost Offices > UCL BEAMS > Faculty of Maths and Physical Sciences UCL > Provost and Vice Provost Offices > UCL BEAMS > Faculty of Maths and Physical Sciences > Dept of Physics and Astronomy |
| URI: | https://discovery.ucl.ac.uk/id/eprint/10123180 |
Loading...
Loading...Loading...Loading...Archive Staff Only
 |
View Item |
