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The year in cardiovascular medicine 2020: arrhythmias

Crijns, HJGM; Prinzen, F; Lambiase, PD; Sanders, P; Brugada, J; (2021) The year in cardiovascular medicine 2020: arrhythmias. European Heart Journal , 42 (5) pp. 499-507. 10.1093/eurheartj/ehaa1091.

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Abstract

Summary of the progress in arrhythmias in 2020. RACE4 and ALL-IN indicated that integrated nurse-led care improves outcomes in AF patients. The same was reported for early rhythm control therapy and cryoablation as initial AF treatment. Subcutaneous ICD was non-inferior to classical transvenous ICD therapy in PRAETORIAN. One mechanistic study showed that autoantibodies against misexpressed actin, keratin, and connexin-43 proteins create a blood-borne biomarker profile enhancing diagnosis of Brugada syndrome. Another mechanistic study indicated that transseptal LV pacing yields similar improvement in contractility as His bundle pacing whilst being more easy to execute. In PRE-DETERMINE a simple-to-use ECG risk score improved risk prediction in patients with ischemic heart disease possibly enhancing appropriate ICD therapy in high risk patients.

Type: Article
Title: The year in cardiovascular medicine 2020: arrhythmias
Location: England
DOI: 10.1093/eurheartj/ehaa1091
Publisher version: https://doi.org/10.1093/eurheartj/ehaa1091
Language: English
Additional information: This version is the author accepted manuscript. For information on re-use, please refer to the publisher’s terms and conditions.
Keywords: Guidelines, Randomized trial, Integrated care, Life style, Atrial fibrillation, Ventricular arrhythmias, Implantable defibrillator, His/left bundle pacing, Cardiogenetics
UCL classification: UCL
UCL > Provost and Vice Provost Offices
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Population Health Sciences
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Population Health Sciences > Institute of Cardiovascular Science
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Population Health Sciences > Institute of Cardiovascular Science > Clinical Science
URI: https://discovery.ucl.ac.uk/id/eprint/10122864
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