Poduval, RK;
Coote, JM;
Mosse, CA;
Finlay, MC;
Desjardins, E;
Papakonstantinou, I;
(2021)
Precision-microfabricated fiber-optic probe for intravascular pressure and temperature sensing.
IEEE Journal of Selected Topics in Quantum Electronics
10.1109/JSTQE.2021.3054727.
(In press).
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Abstract
Small form-factor sensors are widely used in minimally invasive intravascular diagnostic procedures. Manufacturing complexities associated with miniaturizing current fiber-optic probes, particularly for multi-parameter sensing, severely constrain their adoption outside of niche fields. It is especially challenging to rapidly prototype and iterate upon sensor designs to optimize performance for medical devices. In this work, a novel technique to construct a microscale extrinsic fiber-optic sensor with a confined air cavity and sub-micron geometric resolution is presented. The confined air cavity is enclosed between a 3 μm thick pressure-sensitive distal diaphragm and a proximal temperature-sensitive plano-convex microlens segment unresponsive to changes in external pressure. Simultaneous pressure and temperature measurements are possible through optical interrogation via phase-resolved low-coherence interferometry(LCI). Upon characterization in a simulated intravascular environment, we find these sensors capable of detecting pressure changes down to 0.11 mmHg (in the range of 760 to 1060 mmHg) and temperature changes of 0.036°C (in the range 34 to 50°C). By virtue of these sensitivity values suited to intravascular physiological monitoring, and the scope of design flexibility enabled by the precision-fabricated photoresist microstructure, it is envisaged that this technique will enable construction of a wide range of fiber-optic sensors for guiding minimally invasive medical procedures.
| Type: | Article |
|---|---|
| Title: | Precision-microfabricated fiber-optic probe for intravascular pressure and temperature sensing |
| Open access status: | An open access version is available from UCL Discovery |
| DOI: | 10.1109/JSTQE.2021.3054727 |
| Publisher version: | https://dx.doi.org/10.1109/JSTQE.2021.3054727 |
| Language: | English |
| Additional information: | This work is licensed under a Creative Commons Attribution 4.0 License. For more information, see https://creativecommons.org/licenses/by/4.0/ |
| UCL classification: | UCL UCL > Provost and Vice Provost Offices > UCL BEAMS UCL > Provost and Vice Provost Offices > UCL BEAMS > Faculty of Engineering Science UCL > Provost and Vice Provost Offices > UCL BEAMS > Faculty of Engineering Science > Dept of Electronic and Electrical Eng UCL > Provost and Vice Provost Offices > UCL BEAMS > Faculty of Engineering Science > Dept of Med Phys and Biomedical Eng |
| URI: | https://discovery.ucl.ac.uk/id/eprint/10122507 |
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