Yamamoto, AK;
Magerkurth, J;
Mancini, L;
White, M;
Kazan, S;
Miserocchi, A;
McEvoy, A;
... Yousry, T; + view all
(2018)
Intra-operative acquisition of sensorimotor fMRI during glioma resection: evaluation of feasibility and clinical applicability.
In:
Proceedings of the International Society for Magnetic Resonance in Medicine ISMRM 27th Annual Meeting.
(pp. 0595).
ISMRM: Paris, France.
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Abstract
Intra-operative fMRI has the potential to improve neurosurgical outcomes and we have previously shown that the task-related BOLD signal can be acquired under general anaesthesia. Our next goal was to acquire fMRI intra-operatively with the skull open. In 12 patients, we performed 24 acquisitions of a passive sensorimotor paradigm during the resection of their brain tumour. The fMRI data were evaluated by neuroradiologists, assessing its applicability for the provision of a clinical report on the location of sensorimotor activation to the neurosurgeon. 17/24 acquisitions were scored as useful. We conclude that intra-operative fMRI is feasible and produces clinically useful data.
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