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Ammonia: what adult neurologists need to know

Meijer, R; Vivekananda, U; Balestrini, S; Walker, M; Lachmann, R; Haeberle, J; Murphy, E; (2021) Ammonia: what adult neurologists need to know. Practical Neurology , 21 pp. 36-42. 10.1136/practneurol-2020-002654. Green open access

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Abstract

Hyperammonaemia is often encountered in acute neurology and can be the cause of acute or chronic neurological symptoms. Patients with hyperammonaemia may present with seizures or encephalopathy, or may be entirely asymptomatic. The underlying causes are diverse but often straightforward to diagnose, although sometimes require specialist investigations. Haemodialysis or haemo(dia)filtration is the first-line treatment for acute severe hyperammonaemia (of any cause) in an adult. Here we discuss our approach to adult patients with hyperammonaemia identified by a neurologist.

Type: Article
Title: Ammonia: what adult neurologists need to know
Location: England
Open access status: An open access version is available from UCL Discovery
DOI: 10.1136/practneurol-2020-002654
Publisher version: http://dx.doi.org/10.1136/practneurol-2020-002654
Language: English
Additional information: This version is the author accepted manuscript. For information on re-use, please refer to the publisher’s terms and conditions.
Keywords: Coma, epilepsy, metabolic disease
UCL classification: UCL
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Brain Sciences
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Brain Sciences > UCL Queen Square Institute of Neurology
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Brain Sciences > UCL Queen Square Institute of Neurology > Clinical and Experimental Epilepsy
URI: https://discovery.ucl.ac.uk/id/eprint/10122033
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