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The assessment of patients with the antiphospholipid antibody syndrome: where are we now?

Gaspar, P; Cohen, H; Isenberg, DA; (2020) The assessment of patients with the antiphospholipid antibody syndrome: where are we now? Rheumatology , 59 (7) pp. 1489-1494. 10.1093/rheumatology/keaa172. Green open access

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Abstract

The antiphospholipid antibody syndrome (APS), a chronic autoimmune thrombophilia with an increased mortality and morbidity, has been recognized for more than three decades. Unlike other autoimmune rheumatic conditions such as systemic lupus erythematosus, myositis and Sjögren’s syndrome, relatively few attempts have been made to develop activity, damage or disease-specific quality of life indices for APS. In this review of the literature, we consider those attempts that have been made to develop assessment tools for patients with APS, but also reflect upon the nature of the condition, to discuss, in particular, whether an activity index is appropriate for this disease.

Type: Article
Title: The assessment of patients with the antiphospholipid antibody syndrome: where are we now?
Open access status: An open access version is available from UCL Discovery
DOI: 10.1093/rheumatology/keaa172
Publisher version: http://dx.doi.org/10.1093/rheumatology/keaa172
Language: English
Additional information: This version is the author accepted manuscript. For information on re-use, please refer to the publisher’s terms and conditions.
Keywords: antiphospholipid syndrome, assessment, damage index, quality of life, activity index, QUALITY-OF-LIFE, SYSTEMIC-LUPUS-ERYTHEMATOSUS, DISEASE-ACTIVITY, ORGAN DAMAGE, INITIAL VALIDATION, INDEX, MORTALITY, ANTICOAGULANT, RELIABILITY, THROMBOSIS
UCL classification: UCL
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Medical Sciences
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Medical Sciences > Cancer Institute
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Medical Sciences > Cancer Institute > Research Department of Haematology
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Medical Sciences > Div of Medicine
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Medical Sciences > Div of Medicine > Inflammation
URI: https://discovery.ucl.ac.uk/id/eprint/10122018
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