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Whither Magnetic Hyperthermia? A Tentative Roadmap

Rubia-Rodríguez, I; Santana-Otero, A; Spassov, S; Tombácz, E; Johansson, C; De La Presa, P; Teran, FJ; ... Ortega, D; + view all (2021) Whither Magnetic Hyperthermia? A Tentative Roadmap. Materials & Design , 14 (4) , Article 706. 10.3390/ma14040706. Green open access

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Abstract

The scientific community has made great efforts in advancing magnetic hyperthermia for the last two decades after going through a sizeable research lapse from its establishment. All the progress made in various topics ranging from nanoparticle synthesis to biocompatibilization and in vivo testing have been seeking to push the forefront towards some new clinical trials. As many, they did not go at the expected pace. Today, fruitful international cooperation and the wisdom gain after a careful analysis of the lessons learned from seminal clinical trials allow us to have a future with better guarantees for a more definitive takeoff of this genuine nanotherapy against cancer. Deliberately giving prominence to a number of critical aspects, this opinion review offers a blend of state-of-the-art hints and glimpses into the future of the therapy, considering the expected evolution of science and technology behind magnetic hyperthermia.

Type: Article
Title: Whither Magnetic Hyperthermia? A Tentative Roadmap
Location: Switzerland
Open access status: An open access version is available from UCL Discovery
DOI: 10.3390/ma14040706
Publisher version: https://doi.org/10.3390/ma14040706
Language: English
Additional information: This is an open access article distributed under the Creative Commons Attribution License (https://creativecommons.org/licenses/by/4.0/) which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
Keywords: magnetic hyperthermia; magnetic nanoparticles; hysteresis losses; cancer; magnetic particle imaging; theranostics; nanoparticles synthesis; thermometry; standardization; nanotoxicity
UCL classification: UCL
UCL > Provost and Vice Provost Offices > UCL BEAMS
UCL > Provost and Vice Provost Offices > UCL BEAMS > Faculty of Engineering Science
UCL > Provost and Vice Provost Offices > UCL BEAMS > Faculty of Engineering Science > Dept of Chemical Engineering
UCL > Provost and Vice Provost Offices > UCL BEAMS > Faculty of Maths and Physical Sciences
UCL > Provost and Vice Provost Offices > UCL BEAMS > Faculty of Maths and Physical Sciences > Dept of Physics and Astronomy
URI: https://discovery.ucl.ac.uk/id/eprint/10121986
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