Roy, NA;
Bak, JH;
International Brain Laboratory;
Akrami, A;
Brody, CD;
Pillow, JW;
(2021)
Extracting the dynamics of behavior in sensory decision-making experiments.
Neuron
, 109
(4)
597-610.e6.
10.1016/j.neuron.2020.12.004.
Preview |
Text
Psytrack_Manuscript_Draft (4).pdf - Accepted Version Download (15MB) | Preview |
Abstract
Decision-making strategies evolve during training and can continue to vary even in well-trained animals. However, studies of sensory decision-making tend to characterize behavior in terms of a fixed psychometric function that is fit only after training is complete. Here, we present PsyTrack, a flexible method for inferring the trajectory of sensory decision-making strategies from choice data. We apply PsyTrack to training data from mice, rats, and human subjects learning to perform auditory and visual decision-making tasks. We show that it successfully captures trial-to-trial fluctuations in the weighting of sensory stimuli, bias, and task-irrelevant covariates such as choice and stimulus history. This analysis reveals dramatic differences in learning across mice and rapid adaptation to changes in task statistics. PsyTrack scales easily to large datasets and offers a powerful tool for quantifying time-varying behavior in a wide variety of animals and tasks.
| Type: | Article |
|---|---|
| Title: | Extracting the dynamics of behavior in sensory decision-making experiments |
| Location: | United States |
| Open access status: | An open access version is available from UCL Discovery |
| DOI: | 10.1016/j.neuron.2020.12.004 |
| Publisher version: | http://dx.doi.org/10.1016/j.neuron.2020.12.004 |
| Language: | English |
| Additional information: | This version is the author accepted manuscript. For information on re-use, please refer to the publisher’s terms and conditions. |
| Keywords: | behavioral dynamics, learning, psychophysics, sensory decision making |
| UCL classification: | UCL UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Life Sciences UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Life Sciences > The Sainsbury Wellcome Centre |
| URI: | https://discovery.ucl.ac.uk/id/eprint/10121150 |
Archive Staff Only
 |
View Item |
