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Ketogenic diet therapy in infants with epilepsy

Schoeler, NE; Cross, JH; (2020) Ketogenic diet therapy in infants with epilepsy. Paediatrics and Child Health , 30 (10) pp. 356-360. 10.1016/j.paed.2020.07.004. Green open access

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Abstract

Approximately 25% of children with epilepsy are drug-resistant. Lack of seizure control in infants impacts developmental outcome and places a large burden on NHS services, but there are few data to guide optimal treatment in infants with drug-resistant epilepsy. Ketogenic diet therapy is an effective non-pharmacological treatment option for individuals with drug-resistant epilepsy and reports of its use in infants have increased over the last decade. This article gives an overview of use of ketogenic diet therapy in infants with epilepsy, including a history of dietary treatment, evidence for efficacy in infants, patient selection and clinical and dietetic management.

Type: Article
Title: Ketogenic diet therapy in infants with epilepsy
Open access status: An open access version is available from UCL Discovery
DOI: 10.1016/j.paed.2020.07.004
Publisher version: https://doi.org/10.1016/j.paed.2020.07.004
Language: English
Additional information: This version is the author accepted manuscript. For information on re-use, please refer to the publisher’s terms and conditions.
UCL classification: UCL
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Population Health Sciences > UCL GOS Institute of Child Health
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Population Health Sciences > UCL GOS Institute of Child Health > Developmental Neurosciences Dept
URI: https://discovery.ucl.ac.uk/id/eprint/10121029
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