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Rheumatic disease and COVID-19: epidemiology and outcomes

Hyrich, KL; Machado, PM; (2021) Rheumatic disease and COVID-19: epidemiology and outcomes. Nature Reviews Rheumatology , 17 pp. 71-72. 10.1038/s41584-020-00562-2. Green open access

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Abstract

Patients with rheumatoid arthritis, systemic lupus erythematosus or psoriasis, when analysed as a combined group, might have a slightly increased risk of death from COVID-19 compared to those without these diseases, although the role of disease activity and treatment in this risk estimation was not taken into account2. Treatment with cytokine inhibitors could reduce the risk of SARS-SoV-2 infection (as measured by development of SARS-CoV-2 antibodies), although the mechanisms of this protective effect are not clear3. Chronic use of glucocorticoids at moderate or high doses (≥10 mg per day prednisolone or equivalent) is associated with hospitalization for severe COVID-194.

Type: Article
Title: Rheumatic disease and COVID-19: epidemiology and outcomes
Open access status: An open access version is available from UCL Discovery
DOI: 10.1038/s41584-020-00562-2
Publisher version: https://doi.org/10.1038/s41584-020-00562-2
Language: English
Additional information: This version is the author accepted manuscript. For information on re-use, please refer to the publisher's terms and conditions.
Keywords: Rheumatology, Risk factors
UCL classification: UCL
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Brain Sciences
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Brain Sciences > UCL Queen Square Institute of Neurology
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Brain Sciences > UCL Queen Square Institute of Neurology > Department of Neuromuscular Diseases
URI: https://discovery.ucl.ac.uk/id/eprint/10120400
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