Pepys, M;
(2021)
Transthyretin amyloidosis: new answers but many questions.
Journal of Internal Medicine
, 289
(6)
pp. 933-935.
10.1111/joim.13250.
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Abstract
Major recent advances in understanding of systemic transthyretin (ATTR) amyloidosis include the universal recognition that cardiac wild type ATTR amyloidosis is a prevalent cause of fatal heart failure with preserved ejection fraction (HFpEF) and/or fatal arrhythmia in the elderly, predominantly in men. ATTR amyloid cardiomyopathy is strongly associated with carpal tunnel syndrome, caused by wild type ATTR amyloid deposition in the carpal ligaments. The very interesting study by Eldhagen et al in this issue sheds further light on the association between cardiac and ligament ATTR amyloid but tantalisingly leaves several crucial questions unanswered.
| Type: | Article |
|---|---|
| Title: | Transthyretin amyloidosis: new answers but many questions |
| Location: | England |
| Open access status: | An open access version is available from UCL Discovery |
| DOI: | 10.1111/joim.13250 |
| Publisher version: | https://doi.org/10.1111/joim.13250 |
| Language: | English |
| Additional information: | This version is the author accepted manuscript. For information on re-use, please refer to the publisher’s terms and conditions. |
| Keywords: | Amyloidosis |
| UCL classification: | UCL UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Medical Sciences UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Medical Sciences > Div of Medicine UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Medical Sciences > Div of Medicine > Inflammation |
| URI: | https://discovery.ucl.ac.uk/id/eprint/10119877 |
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