Martins, PN;
Clavien, P-A;
Jalan, R;
Ghinolfi, D;
(2021)
A Call for Randomization in Clinical Trials of Liver Machine Perfusion Preservation.
Hepatology
, 73
(6)
pp. 2586-2591.
10.1002/hep.31686.
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Abstract
Liver transplantation is a lifesaving operation for patients with advanced liver failure. Although mortality from liver disease continues to increase, the number of available grafts remain relatively unchanged, leading to the death of about 15‐30% patients on the waiting list. Therefore, transplant teams have resorted to using marginal organs with often poorer outcomes.
| Type: | Article |
|---|---|
| Title: | A Call for Randomization in Clinical Trials of Liver Machine Perfusion Preservation |
| Location: | United States |
| Open access status: | An open access version is available from UCL Discovery |
| DOI: | 10.1002/hep.31686 |
| Publisher version: | https://doi.org/10.1002/hep.31686 |
| Language: | English |
| Additional information: | This version is the author accepted manuscript. For information on re-use, please refer to the publisher’s terms and conditions. |
| Keywords: | clinical trials, liver machine preservation, normothermic machine perfusion, ex‐situ preservation, liver transplantation, randomized controlled trials, study design, bias, study endpoints, biomarkers, limitations, outcomes |
| UCL classification: | UCL UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Medical Sciences UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Medical Sciences > Div of Medicine UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Medical Sciences > Div of Medicine > Inst for Liver and Digestive Hlth |
| URI: | https://discovery.ucl.ac.uk/id/eprint/10119247 |
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