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Relationship between loneliness, social isolation and modifiable risk factors for cardiovascular disease: a latent class analysis

Bu, F; Steptoe, A; Fancourt, D; (2021) Relationship between loneliness, social isolation and modifiable risk factors for cardiovascular disease: a latent class analysis. Journal of Epidemiology and Community Health 10.1136/jech-2020-215539. (In press). Green open access

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Abstract

Background: There is growing research into the effects of psychological and social factors such as loneliness and isolation on cardiovascular disease (CVD). However, it is unclear whether individuals with particular clusters of CVD risk factors are more strongly affected by loneliness and isolation. This study aimed to identify latent clustering of modifiable risk factors among adults aged 50+ and explore the relationship between loneliness, social isolation and risk factor patterns. Methods: Data from 8218 adults of English Longitudinal Study of Ageing were used in latent class analyses to identify latent classes of cardiovascular risk factors and predictors of class membership. Results: There were four latent classes: low-risk (30.2%), high-risk (15.0%), clinical-risk (42.6%) and lifestyle-risk (12.2%) classes. Loneliness was associated with a greater risk of being in the high-risk class (relative risk ratio (RRR) 2.40, 95%CI 2.40 to 1.96) and lifestyle-risk class (RRR 1.36, 95%CI 1.10 to 1.67) and a lower risk of being in the clinical-risk class (RRR 0.84, 95%CI 0.72 to 0.98) relative to the low-risk class. Social disengagement, living alone and low social contact were also differentially associated with latent class memberships. Conclusion: These findings supplement our existing knowledge of modifiable risk factors for CVD by showing how risk factors cluster together and how the risk patterns are related to social factors, offering important implications for clinical practice and preventive interventions

Type: Article
Title: Relationship between loneliness, social isolation and modifiable risk factors for cardiovascular disease: a latent class analysis
Location: England
Open access status: An open access version is available from UCL Discovery
DOI: 10.1136/jech-2020-215539
Publisher version: https://doi.org/10.1136/jech-2020-215539
Language: English
Additional information: This is an open access article distributed in accordance with the Creative Commons Attribution 4.0 Unported (CC BY 4.0) license, which permits others to copy, redistribute, remix, transform and build upon this work for any purpose, provided the original work is properly cited, a link to the licence is given, and indication of whether changes were made. See: https://creativecommons.org/licenses/by/4.0/.
UCL classification: UCL
UCL > Provost and Vice Provost Offices
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Population Health Sciences
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Population Health Sciences > Institute of Epidemiology and Health
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Population Health Sciences > Institute of Epidemiology and Health > Behavioural Science and Health
URI: https://discovery.ucl.ac.uk/id/eprint/10118815
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