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Fatal autonomic failure due to premanifesting Parkinson's disease only diagnosed at autopsy

Bodi, I; Hagen, EM; Ingle, GT; Lunn, MP; (2020) Fatal autonomic failure due to premanifesting Parkinson's disease only diagnosed at autopsy. Clinical Case Reports , 8 (10) pp. 1997-1999. 10.1002/ccr3.3042. Green open access

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Abstract

A 46‐year‐old male had 11‐year history of cryptic autonomic dysfunction. He developed a fatal autonomic failure with diffuse hypoxic brain injury. Histology examination of medulla oblongata and the celiac ganglion revealed many α‐synuclein immunoreactive Lewy bodies confirming the diagnosis of premanifesting Parkinson's disease (PD). PNS involvement in PD is underappreciated.

Type: Article
Title: Fatal autonomic failure due to premanifesting Parkinson's disease only diagnosed at autopsy
Open access status: An open access version is available from UCL Discovery
DOI: 10.1002/ccr3.3042
Publisher version: https://doi.org/10.1002/ccr3.3042
Language: English
Additional information: This is an open access article under the CC BY license (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
UCL classification: UCL
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Brain Sciences
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Brain Sciences > UCL Queen Square Institute of Neurology
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Brain Sciences > UCL Queen Square Institute of Neurology > Brain Repair and Rehabilitation
URI: https://discovery.ucl.ac.uk/id/eprint/10118242
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