UCL Discovery
UCL home » Library Services » Electronic resources » UCL Discovery

Cross-sectional and longitudinal associations between psychotic and depressive symptoms in depressed adolescents

Kehinde, F; Bharmal, AV; Goodyer, IM; Kelvin, R; Dubicka, B; Midgley, N; Fonagy, P; ... Wilkinson, P; + view all (2021) Cross-sectional and longitudinal associations between psychotic and depressive symptoms in depressed adolescents. European Child and Adolescent Psychiatry (In press).

[img] Text
Fonagy_ADAPT IMPACT Psychosis 5Dec20 final.pdf - Accepted version
Access restricted to UCL open access staff until 3 June 2021.

Download (294kB)

Abstract

Adults with Major Depressive Disorder (MDD) with psychotic features (delusions and/or hallucinations) have more severe symptoms and a worse prognosis. Sub-clinical psychotic symptoms are more common in adolescents than adults. However, the effects of psychotic symptoms on outcome of depressive symptoms have not been well-studied in adolescents. Depressed adolescents aged 11-17 with and without psychotic symptoms were compared on depression severity scores at baseline and at 28 or 42 week follow-up in two large UK cohorts. Psychotic symptoms were weakly associated with more severe depression at baseline in both cohorts. At follow-up, baseline psychotic symptoms were only associated with depressive symptoms in one sample; in the other, the effect size was close to zero. This supports the DSM5 system of psychotic symptoms being a separate code to severity rather than the ICD10 system which only allows the diagnosis of psychotic depression with severe depression. There was no clear support for psychotic symptoms being a baseline marker of treatment response.

Type: Article
Title: Cross-sectional and longitudinal associations between psychotic and depressive symptoms in depressed adolescents
Publisher version: https://www.springer.com/journal/787
Language: English
Additional information: This version is the author accepted manuscript. For information on re-use, please refer to the publisher’s terms and conditions.
Keywords: Psychotic symptoms, adolescence, unipolar depression, depression severity
UCL classification: UCL
UCL > Provost and Vice Provost Offices
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Brain Sciences
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Brain Sciences > Div of Psychology and Lang Sciences
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Brain Sciences > Div of Psychology and Lang Sciences > Clinical, Edu and Hlth Psychology
URI: https://discovery.ucl.ac.uk/id/eprint/10116984
Downloads since deposit
1Download
Download activity - last month
Download activity - last 12 months
Downloads by country - last 12 months

Archive Staff Only

View Item View Item