Testi, I;
Agrawal, R;
Mehta, S;
Basu, S;
Nguyen, Q;
Pavesio, C;
Gupta, V;
(2020)
Ocular tuberculosis: Where are we today?
Indian Journal of Ophthalmology
, 68
(9)
pp. 1808-1817.
10.4103/ijo.IJO_1451_20.
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Abstract
Diagnosis and management of ocular tuberculosis (OTB) poses a significant challenge. Mixed ocular tissue involvement and lack of agreement on best practice diagnostic tests together with the global variations in therapeutic management contributed to the existing uncertainties regarding the outcome of the disease. The current review aims to update recent progress on OTB. In particular, the Collaborative Ocular Tuberculosis Study (COTS) group recently standardized a nomenclature system for defining clinical phenotypes, and also proposed consensus guidelines and an algorithmic approach for management of different clinical phenotypes of OTB. Recent developments in experimental research and innovations in molecular diagnostics and imaging technology have provided a new understanding in the pathogenesis and natural history of the disease.
| Type: | Article |
|---|---|
| Title: | Ocular tuberculosis: Where are we today? |
| Open access status: | An open access version is available from UCL Discovery |
| DOI: | 10.4103/ijo.IJO_1451_20 |
| Publisher version: | https://doi.org/10.4103/ijo.IJO_1451_20 |
| Language: | English |
| Additional information: | This version is the author accepted manuscript. For information on re-use, please refer to the publisher’s terms and conditions. |
| Keywords: | Antitubercular therapy, collaborative ocular tuberculosis study (COTS), COTS CON nomenclature, etiopathogenesis, multimodal imaging, ocular tuberculosis, tubercular uveitis |
| UCL classification: | UCL UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Brain Sciences UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Brain Sciences > Institute of Ophthalmology |
| URI: | https://discovery.ucl.ac.uk/id/eprint/10116085 |
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