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The Collaborative Ocular Tuberculosis Study (COTS) Consensus (CON) Group Meeting Proceedings

Agrawal, R; Testi, I; Mahajan, S; Yuen, YS; Agarwal, A; Rousselot, A; Raje, D; ... Gupta, V; + view all (2020) The Collaborative Ocular Tuberculosis Study (COTS) Consensus (CON) Group Meeting Proceedings. Ocular Immunology and Inflammation 10.1080/09273948.2020.1716025. (In press). Green open access

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Abstract

An international, expert led consensus initiative was set up by the Collaborative Ocular Tuberculosis Study (COTS) group to develop systematic, evidence, and experience-based recommendations for the treatment of ocular TB using a modified Delphi technique process. In the first round of Delphi, the group identified clinical scenarios pertinent to ocular TB based on five clinical phenotypes (anterior uveitis, intermediate uveitis, choroiditis, retinal vasculitis, and panuveitis). Using an interactive online questionnaires, guided by background knowledge from published literature, 486 consensus statements for initiating ATT were generated and deliberated amongst 81 global uveitis experts. The median score of five was considered reaching consensus for initiating ATT. The median score of four was tabled for deliberation through Delphi round 2 in a face-to-face meeting. This report describes the methodology adopted and followed through the consensus process, which help elucidate the guidelines for initiating ATT in patients with choroidal TB.

Type: Article
Title: The Collaborative Ocular Tuberculosis Study (COTS) Consensus (CON) Group Meeting Proceedings
Open access status: An open access version is available from UCL Discovery
DOI: 10.1080/09273948.2020.1716025
Publisher version: https://doi.org/10.1080/09273948.2020.1716025
Language: English
Additional information: This version is the author accepted manuscript. For information on re-use, please refer to the publisher’s terms and conditions.
Keywords: Antitubercular therapy, choroiditis, Collaborative Ocular Tuberculosis Study Consensus (COTS CON), consensus guidelines, ocular tuberculosis
UCL classification: UCL
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Brain Sciences
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Brain Sciences > Institute of Ophthalmology
URI: https://discovery.ucl.ac.uk/id/eprint/10116073
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