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Nano-Modified Titanium Implant Materials: A Way Toward Improved Antibacterial Properties

Liu, J; Liu, J; Attarilar, S; Wang, C; Tamaddon, M; Yang, C; Xie, K; ... Tang, Y; + view all (2020) Nano-Modified Titanium Implant Materials: A Way Toward Improved Antibacterial Properties. Frontiers in Bioengineering and Biotechnology , 8 , Article 576969. 10.3389/fbioe.2020.576969. Green open access

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Abstract

Titanium and its alloys have superb biocompatibility, low elastic modulus, and favorable corrosion resistance. These exceptional properties lead to its wide use as a medical implant material. Titanium itself does not have antibacterial properties, so bacteria can gather and adhere to its surface resulting in infection issues. The infection is among the main reasons for implant failure in orthopedic surgeries. Nano-modification, as one of the good options, has the potential to induce different degrees of antibacterial effect on the surface of implant materials. At the same time, the nano-modification procedure and the produced nanostructures should not adversely affect the osteogenic activity, and it should simultaneously lead to favorable antibacterial properties on the surface of the implant. This article scrutinizes and deals with the surface nano-modification of titanium implant materials from three aspects: nanostructures formation procedures, nanomaterials loading, and nano-morphology. In this regard, the research progress on the antibacterial properties of various surface nano-modification of titanium implant materials and the related procedures are introduced, and the new trends will be discussed in order to improve the related materials and methods.

Type: Article
Title: Nano-Modified Titanium Implant Materials: A Way Toward Improved Antibacterial Properties
Open access status: An open access version is available from UCL Discovery
DOI: 10.3389/fbioe.2020.576969
Publisher version: https://doi.org/10.3389/fbioe.2020.576969
Language: English
Additional information: © 2020 Liu, Liu, Attarilar, Wang, Tamaddon, Yang, Xie, Yao, Wang, Liu and Tang. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
Keywords: bactericidal, nanostructure, antibacterial, nanoparticles, titanium-implants
UCL classification: UCL
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Medical Sciences
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Medical Sciences > Div of Surgery and Interventional Sci
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Medical Sciences > Div of Surgery and Interventional Sci > Department of Ortho and MSK Science
URI: https://discovery.ucl.ac.uk/id/eprint/10115646
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