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Effective modeling of high-energy laboratory-based x-ray phase contrast imaging utilizing absorption masks or gratings

Buchanan, I; Kallon, G; Beckenbach, T; Schulz, J; Endrizzi, M; Olivo, A; (2020) Effective modeling of high-energy laboratory-based x-ray phase contrast imaging utilizing absorption masks or gratings. Journal of Applied Physics , 128 (21) , Article 214503. 10.1063/5.0024475. Green open access

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Abstract

Model refinements for the edge illumination x-ray phase contrast imaging method have been developed to improve simulation accuracy for high energy, polychromatic beams. High-energy x rays are desirable in imaging due to their penetrative power and, for biological samples, their lower dose deposition rate. Accurate models of such scenarios are required for designing appropriate imaging systems and to predict signal strength in complex settings such as clinical imaging or industrial quality assurance. When using optical components appropriate for high-energy x rays in a non-synchrotron setting, system performance was observed to deviate from that predicted by existing models. In this work, experimental data utilizing increasing thicknesses of a known filter material are used to illustrate the limitations of existing models and as validation for the new modeling features. Angular filtration of the cone beam was observed to be the most significant effect; however, specific features of the source and detector are also shown to affect system performance. We conclude by showing that a significantly improved agreement between experimental and simulated data is obtained with the refined model compared to previously existing ones.

Type: Article
Title: Effective modeling of high-energy laboratory-based x-ray phase contrast imaging utilizing absorption masks or gratings
Open access status: An open access version is available from UCL Discovery
DOI: 10.1063/5.0024475
Publisher version: https://doi.org/10.1063/5.0024475
Language: English
Additional information: This version is the version of record. For information on re-use, please refer to the publisher’s terms and conditions.
Keywords: Scattering theory, X-ray phase contrast imaging, Physical optics, Septum, High-energy X rays, Quality assurance, Geometrical optics, Generalized functions, Radiometry, Optical metrology
UCL classification: UCL
UCL > Provost and Vice Provost Offices > UCL BEAMS
UCL > Provost and Vice Provost Offices > UCL BEAMS > Faculty of Engineering Science
UCL > Provost and Vice Provost Offices > UCL BEAMS > Faculty of Engineering Science > Dept of Med Phys and Biomedical Eng
URI: https://discovery.ucl.ac.uk/id/eprint/10115159
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