UCL Discovery
UCL home » Library Services » Electronic resources » UCL Discovery

Continuous flow processing as a tool for the generation of terpene-derived monomer libraries

Galaverna, R; Fernandes, LP; Browne, DL; Pastre, JC; (2019) Continuous flow processing as a tool for the generation of terpene-derived monomer libraries. Reaction Chemistry & Engineering , 4 (2) pp. 362-367. 10.1039/c8re00237a. Green open access

[thumbnail of c8re00237a pp.pdf]
Preview
Text
c8re00237a pp.pdf - Accepted Version

Download (640kB) | Preview

Abstract

We report the development of a continuous flow approach for the preparation of two bio-derived monomer libraries. A small range of terpenes (ocimene, myrcene, α-terpinene, α-phellandrene, isoprene, and farnesene) have been used as the base set for the library, with the first library derived from a Diels–Alder reaction with the platform chemical maleic anhydride. The second library requires the derivatization of the first through a hydrogenation reaction. The potential for scale-up of both libraries has been demonstrated, with the Diels–Alder process delivering 10.5 grams of the product in 3 hours and the hydrogenation process delivering 10 grams of the material in 16 hours.

Type: Article
Title: Continuous flow processing as a tool for the generation of terpene-derived monomer libraries
Open access status: An open access version is available from UCL Discovery
DOI: 10.1039/c8re00237a
Publisher version: https://doi.org/10.1039/C8RE00237A
Language: English
Additional information: This version is the author accepted manuscript. For information on re-use, please refer to the publisher’s terms and conditions.
Keywords: Science & Technology, Physical Sciences, Technology, Chemistry, Multidisciplinary, Engineering, Chemical, Chemistry, Engineering, GASEOUS AMMONIA, POLYMERIZATION, HYDROGENATION, COPOLYMERS, CHEMICALS, BIOMASS, GREEN
UCL classification: UCL
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Life Sciences
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Life Sciences > UCL School of Pharmacy
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Life Sciences > UCL School of Pharmacy > Pharma and Bio Chemistry
URI: https://discovery.ucl.ac.uk/id/eprint/10114328
Downloads since deposit
98Downloads
Download activity - last month
Download activity - last 12 months
Downloads by country - last 12 months

Archive Staff Only

View Item View Item