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Cancer risk in children born after assisted reproductive technology

Arshad, A; Sutcliffe, AG; (2020) Cancer risk in children born after assisted reproductive technology. Gynakologische Endokrinologie , 18 (4) pp. 226-230. 10.1007/s10304-020-00334-x. Green open access

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Abstract

The influence of assisted reproductive technologies (ART) on the risk of childhood cancer is poorly understood. We sought to summarise the current literature as to the risk of cancer in children born from ART. Overall, we identified that the current evidence is divergent, with the results of several cohort studies and meta-analyses on this subject ranging from there being no risk or to there being an increased risk from being conceived by ART. Further large-scale cohort studies to determine the influence of ART on cancer risk are required. If a valid risk is present, experimental studies are necessary to determine whether this risk is associated with the use of fertility drugs or is due to the parental infertility.

Type: Article
Title: Cancer risk in children born after assisted reproductive technology
Open access status: An open access version is available from UCL Discovery
DOI: 10.1007/s10304-020-00334-x
Publisher version: https://doi.org/10.1007/s10304-020-00334-x
Language: English
Additional information: This version is the author accepted manuscript. For information on re-use, please refer to the publisher's terms and conditions.
UCL classification: UCL
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Population Health Sciences
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Population Health Sciences > UCL GOS Institute of Child Health
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Population Health Sciences > UCL GOS Institute of Child Health > Population, Policy and Practice Dept
URI: https://discovery.ucl.ac.uk/id/eprint/10113540
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