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Vat photopolymerization 3D printing for advanced drug delivery and medical device applications

Xu, X; Awad, A; Martinez, PR; Gaisford, S; Goyanes, A; Basit, AW; (2021) Vat photopolymerization 3D printing for advanced drug delivery and medical device applications. Journal of Controlled Release , 329 pp. 743-757. 10.1016/j.jconrel.2020.10.008. Green open access

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Abstract

Three-dimensional (3D) printing is transforming manufacturing paradigms within healthcare. Vat photopolymerization 3D printing technology combines the benefits of high resolution and favourable printing speed, offering a sophisticated approach to fabricate bespoke medical devices and drug delivery systems. Herein, an overview of the vat polymerization techniques, their unique applications in the fields of drug delivery and medical device fabrication, material examples and the advantages they provide within healthcare, is provided. The outstanding challenges and drawbacks presented by this technology are also discussed. It is forecast that the adoption of 3D printing could pave the way for a personalised health system, advancing from traditional treatments pathways towards digital healthcare and streamlining a new cyber era.

Type: Article
Title: Vat photopolymerization 3D printing for advanced drug delivery and medical device applications
Open access status: An open access version is available from UCL Discovery
DOI: 10.1016/j.jconrel.2020.10.008
Publisher version: https://doi.org/10.1016/j.jconrel.2020.10.008
Language: English
Additional information: This version is the author accepted manuscript. For information on re-use, please refer to the publisher’s terms and conditions.
Keywords: Additive manufacturing; Photopolymerisation; Stereolithography; Stereolithographic printing; 3D printed drug products; Personalized pharmaceuticals and medicines
UCL classification: UCL
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Life Sciences
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Life Sciences > UCL School of Pharmacy
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Life Sciences > UCL School of Pharmacy > Pharmaceutics
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Population Health Sciences > UCL GOS Institute of Child Health
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Population Health Sciences > UCL GOS Institute of Child Health > Genetics and Genomic Medicine Dept
URI: https://discovery.ucl.ac.uk/id/eprint/10112242
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