UCL Discovery
UCL home » Library Services » Electronic resources » UCL Discovery

Delivering low-dose CT screening for lung cancer: a pragmatic approach

Horst, C; Dickson, JL; Tisi, S; Ruparel, M; Nair, A; Devaraj, A; Janes, SM; (2020) Delivering low-dose CT screening for lung cancer: a pragmatic approach. Thorax , 75 (10) pp. 831-832. 10.1136/thoraxjnl-2020-215131. Green open access

[thumbnail of PDF Manuscript re-resubmission 17.6.20.pdf]
Preview
Text
PDF Manuscript re-resubmission 17.6.20.pdf - Accepted Version

Download (1MB) | Preview

Abstract

Lung cancer kills an estimated 35 000 people in the UK every year. Despite the improvements in treating late-stage disease, lung cancer outcomes have changed little in the last 40 years. Low-dose CT (LDCT) screening for lung cancer reduces lung cancer mortality by 20%–24% and all-cause mortality by 7%.1 2 Lung cancer screening (LCS) however remains contentious, particularly how to implement it in an efficient and efficacious way. This contention extends to the potential costs of screening—financial to the National Health Service (NHS), and physical and psychological harms to patients. These concerns are particularly relevant to how we manage both the findings we aim to detect through screening (pulmonary nodules) and those we pick up inadvertently (incidental findings). The SUMMIT Study is the largest CT screening study in Europe and a key endpoint is detailing the feasibility of delivering CT screening across a complete population within the NHS. We present here SUMMIT’s approach to nodule and incidental findings management, a pragmatic model that is neither overly burdensome nor unsafe and provides a practical solution to some of the challenges of LDCT LCS.

Type: Article
Title: Delivering low-dose CT screening for lung cancer: a pragmatic approach
Location: England
Open access status: An open access version is available from UCL Discovery
DOI: 10.1136/thoraxjnl-2020-215131
Publisher version: http://dx.doi.org/10.1136/thoraxjnl-2020-215131
Language: English
Additional information: This version is the author accepted manuscript. For information on re-use, please refer to the publisher's terms and conditions.
UCL classification: UCL
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Medical Sciences
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Medical Sciences > Div of Medicine
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Medical Sciences > Div of Medicine > Respiratory Medicine
URI: https://discovery.ucl.ac.uk/id/eprint/10112039
Downloads since deposit
0Downloads
Download activity - last month
Download activity - last 12 months
Downloads by country - last 12 months

Archive Staff Only

View Item View Item