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The systemic autoinflammatory disorders for dermatologists. Part 1: overview

Oldham, J; Lachmann, HJ; (2020) The systemic autoinflammatory disorders for dermatologists. Part 1: overview. Clinical and Experimental Dermatology 10.1111/ced.14250. (In press). Green open access

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Abstract

The systemic autoinflammatory disorders (SAIDs) or periodic fever syndromes are disorders of innate immunity, which can be inherited or acquired. They are almost all very rare and easily overlooked; typically, patients will have seen multiple specialities prior to diagnosis, so a high level of clinical suspicion is key. It is important to note that these are ‘high‐value’ diagnoses as the majority of these syndromes can be very effectively controlled, dramatically improving quality of life and providing protection against the development of irreversible complications such as AA amyloidosis. In this article, we take an overview of SAIDs and look at the common features; in Part 2, we take a more in‐depth look at the better recognized or more dermatologically relevant conditions.

Type: Article
Title: The systemic autoinflammatory disorders for dermatologists. Part 1: overview
Location: England
Open access status: An open access version is available from UCL Discovery
DOI: 10.1111/ced.14250
Publisher version: https://doi.org/10.1111/ced.14250
Language: English
Additional information: Copyright © 2020 The Authors. Clinical and Experimental Dermatology published by John Wiley & Sons Ltd on behalf of British Association of Dermatologists. This is an open access article under the terms of the Creative Commons Attribution‐NonCommercial License (http://creativecommons.org/licenses/by-nc/4.0/), which permits use, distribution and reproduction in any medium, provided the original work is properly cited and is not used for commercial purposes.
UCL classification: UCL
UCL > Provost and Vice Provost Offices
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Medical Sciences
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Medical Sciences > Div of Medicine
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Medical Sciences > Div of Medicine > Inflammation
URI: https://discovery.ucl.ac.uk/id/eprint/10111051
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