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The multidisciplinary management of oligometastases from colorectal cancer: a narrative review

Chandy, ETJ; Saxby, HJ; Pang, JW; Sharma, RA; (2020) The multidisciplinary management of oligometastases from colorectal cancer: a narrative review. Annals of Palliative Medicine 10.21037/apm-20-919. (In press). Green open access

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Abstract

In the United States of America, almost 150,000 people are estimated to be diagnosed with colorectal cancer in 2020 and up to 35% of those are expected to present with oligometastatic disease. The term ‘oligometastasis’ was first used in 1995, however surgical literature describing liver resection for colorectal cancer dates back to the 1940s. Five-year survival rates of up to 42% with surgery alone for solitary lesions are reported. Modern trials have demonstrated median overall survival rates of over 80 months for patients with colorectal liver metastases treated with perioperative chemotherapy. Colorectal liver metastases have accordingly been described as ‘proof of concept’ for the oligometastatic theory.

Type: Article
Title: The multidisciplinary management of oligometastases from colorectal cancer: a narrative review
Location: China
Open access status: An open access version is available from UCL Discovery
DOI: 10.21037/apm-20-919
Publisher version: https://doi.org/10.21037/apm-20-919
Language: English
Additional information: This is an Open Access article distributed in accordance with the Creative Commons Attribution-NonCommercial-NoDerivs 4.0 International License (CC BY-NC-ND 4.0), which permits the noncommercial replication and distribution of the article with the strict proviso that no changes or edits are made and the original work is properly cited (including links to both the formal publication through the relevant DOI and the license). See: https://creativecommons.org/licenses/by-nc-nd/4.0/.
Keywords: Radiofrequency ablation (RFA); liver resection; stereotactic ablative body radiotherapy (SABR); transarterial chemotherapy (TACE); selective internal radiotherapy (SIRT)
UCL classification: UCL
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Medical Sciences
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Medical Sciences > Cancer Institute
URI: https://discovery.ucl.ac.uk/id/eprint/10110238
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