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Investigation of changes in the oral microflora of children with time and their possible relationship to caries

Win, Myo; (1992) Investigation of changes in the oral microflora of children with time and their possible relationship to caries. Masters thesis (M.Phil), UCL (University College London). Green open access

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Abstract

Past study of the microbial aetiology of dental caries was often focussed on particular species. Most studies have been cross-sectional, either confined to saliva or plaque samples. In the latter, fissure plaque has been studied less than other types although fissures are the most common site for caries. A study of fissure plaque and salivary microflora was conducted over a 12 month period in a group of 58 children aged 6-8 years. No statistically significant differences were seen in the microflora in relation to caries but some trends were apparent. There was a consistent trend for the anaerobic count to be higher in plaque from carious sites and for Actinomyces to be detected in higher proportions from sites which remained caries-free. The ratio of aerobic to anaerobic counts was higher in plaque from caries-free sites. In contrast, the ratio was less variable and showed little evidence of relationship to caries when saliva was studied. A higher ratio of S. mutans to Actinomyces was found from carious sampling sites. The ratio was also higher samples of children who developed caries but on only two of sampling occasions. in plaque in saliva the three The oral microflora is complex and includes a large number of interacting bacterial species. The two relationships studied in this investigation showed as much relationship to caries as did any one species or group. Results from saliva samples proved more difficult to interpret than did those from plaque and may have been influenced more by the nature of saliva.

Type: Thesis (Masters)
Qualification: M.Phil
Title: Investigation of changes in the oral microflora of children with time and their possible relationship to caries
Open access status: An open access version is available from UCL Discovery
Language: English
Additional information: Thesis digitised by ProQuest.
Keywords: Health and environmental sciences
URI: https://discovery.ucl.ac.uk/id/eprint/10108214
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