UCL Discovery
UCL home » Library Services » Electronic resources » UCL Discovery

Strength of patient cohorts and biobanks for cardiomyopathy research

de Boer, RA; Nijenkamp, LLAM; Silljé, HHW; Eijgenraam, TR; Parbhudayal, R; van Driel, B; Huurman, R; ... van der Velden, J; + view all (2020) Strength of patient cohorts and biobanks for cardiomyopathy research. Netherlands Heart Journal , 28 pp. 50-56. 10.1007/s12471-020-01456-4. Green open access

[thumbnail of Boer2020_Article_StrengthOfPatientCohortsAndBio.pdf]
Preview
Text
Boer2020_Article_StrengthOfPatientCohortsAndBio.pdf - Published Version

Download (1MB) | Preview

Abstract

In 2011 the Netherlands Heart Foundation allocated funding (CVON, Cardiovasculair Onderzoek Nederland) to stimulate collaboration between clinical and preclinical researchers on specific areas of research. One of those areas involves genetic heart diseases, which are frequently caused by pathogenic variants in genes that encode sarcomere proteins. In 2014, the DOSIS (Determinants of susceptibility in inherited cardiomyopathy: towards novel therapeutic approaches) consortium was initiated, focusing their research on secondary disease hits involved in the onset and progression of cardiomyopathies. Here we highlight several recent observations from our consortium and collaborators which may ultimately be relevant for clinical practice.

Type: Article
Title: Strength of patient cohorts and biobanks for cardiomyopathy research
Open access status: An open access version is available from UCL Discovery
DOI: 10.1007/s12471-020-01456-4
Publisher version: https://doi.org/10.1007/s12471-020-01456-4
Language: English
Additional information: This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/.
Keywords: Cardiomyopathies, Gene variants, Patient cohorts
UCL classification: UCL
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Population Health Sciences > Institute of Health Informatics
URI: https://discovery.ucl.ac.uk/id/eprint/10108047
Downloads since deposit
32Downloads
Download activity - last month
Download activity - last 12 months
Downloads by country - last 12 months

Archive Staff Only

View Item View Item