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Sensori-motor integration during different finger movements and evidence for reorganisation in subjects with a chronic partial nerve entrapment of the median nerve at the wrist in man

Turner, Louise Carol; (2003) Sensori-motor integration during different finger movements and evidence for reorganisation in subjects with a chronic partial nerve entrapment of the median nerve at the wrist in man. Doctoral thesis (Ph.D), UCL (University College London). Green open access

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Abstract

In part A of the thesis, experiments were performed to determine whether the reflex effects of digital nerve stimulation on first dorsal interosseous muscle (1DI) are contextually influenced. It was found that voluntary and passive finger movement significantly reduced the size of the transcortical E2 reflex component. Reflex components I1 and E1 were unaltered. The simultaneously recorded contralateral somatosensory cortical evoked potential (SEP) was significantly reduced, suggesting that 'gating' of the afferent input to sensory cortex is involved in reducing the size of the E2 reflex component. The reduction in the cortical SEP components observed during passive finger movement suggests that sensory feedback from the periphery contributes to 'gating' of the afferent input. Subsequent experiments involving attentive and non-attentive finger tasks were performed. It was found that the E2 and I1 components of the CMR and cortical SEP components were selectively altered in a task dependent manner. The E1 reflex component was unaffected. In the final experiment, the reflex effects of distant digital nerve stimulation (little finger) on 1DI during two movement tasks were examined. It was found that the transcortical E2 reflex component radiated in a task dependent manner. Reflex components E1 and I1 were unaltered. In part B, recordings were obtained from subjects with a chronic partial nerve entrapment of the median nerve at the wrist (C.P.N.E). The aim of these experiments was to determine whether the reflex effects of digital nerve stimulation on 1DI is reorganised in the hand in response to the C.P.N.E. It was found that the pattern of the reflex effects of digital nerve stimulation in 1DI was altered in the subjects with C.P.N.E. Stimulation of a distant (little) finger produced clear reflex changes in the 1DI muscle not evident in healthy control subjects, showing that reflex reorganisation has occurred following C.P.N.E.

Type: Thesis (Doctoral)
Qualification: Ph.D
Title: Sensori-motor integration during different finger movements and evidence for reorganisation in subjects with a chronic partial nerve entrapment of the median nerve at the wrist in man
Open access status: An open access version is available from UCL Discovery
Language: English
Additional information: Thesis digitised by ProQuest.
Keywords: Biological sciences; Sensori-motor integration
URI: https://discovery.ucl.ac.uk/id/eprint/10107303
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